Diospyros virginiana, or American persimmon, prefers full sun and well-drained soil for healthy growth. Ensure consistent watering, particularly during dry periods, to keep the soil moist. Prune in late winter to enhance structure and airflow by removing dead or congested branches. Apply mulch to conserve soil moisture and reduce weed competition. Fertilize once a year with a balanced fertilizer to encourage robust growth and fruit development.