Plant Little Joe Pye Weed in full sun to partial shade. Choose well-drained, moist soil. Space plants about 2-3 feet apart. Water regularly, especially during dry spells, to keep the soil consistently moist. Fertilize in early spring with a balanced fertilizer. Deadhead spent flowers to encourage more blooms. Cut back stems to the ground in late fall or early spring to promote healthy growth. Divide clumps every 3-4 years in early spring to maintain vigor.